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Desmoplastic melanoma
Pronunciation
Definition 1
A rare form of malignant melanoma marked by nonpigmented lesions on sun-exposed areas of the body, most commonly on the head and neck. (NCI Dictionary)
Definition 2
A melanoma of the skin characterized by a proliferation of atypical spindled melanocytes in the dermis, in a background of abundant collagen. It usually presents as an amelanotic raised nodular lesion. (NCI Thesaurus)
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Causing or forming adhesions or fibrous connective tissue within a tumor.
Desmoplakin (2871 aa, ~332 kDa) is encoded by the human DSP gene. This protein is involved in the maintenance of desmosome…
