| Library / English Dictionary |
DETERMINANT
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A determining or causal element or factor
Example:
education is an important determinant of one's outlook on life
Synonyms:
causal factor; determinant; determinative; determiner; determining factor
Classified under:
Nouns denoting cognitive processes and contents
Hypernyms ("determinant" is a kind of...):
cognitive factor (something immaterial (as a circumstance or influence) that contributes to producing a result)
Hyponyms (each of the following is a kind of "determinant"):
clincher; decisive factor (a point or fact or remark that settles something conclusively)
influence (a cognitive factor that tends to have an effect on what you do)
Derivation:
determinant (having the power or quality of deciding)
determine (shape or influence; give direction to)
Sense 2
Meaning:
A square matrix used to solve simultaneous equations
Classified under:
Nouns denoting groupings of people or objects
Hypernyms ("determinant" is a kind of...):
square matrix (a matrix with the same number of rows and columns)
Sense 3
Meaning:
The site on the surface of an antigen molecule to which an antibody attaches itself
Synonyms:
antigenic determinant; determinant; epitope
Classified under:
Hypernyms ("determinant" is a kind of...):
site; situation (physical position in relation to the surroundings)
Domain category:
immunology (the branch of medical science that studies the body's immune system)
Holonyms ("determinant" is a part of...):
antigen (any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies))
II. (adjective)
Sense 1
Meaning:
Having the power or quality of deciding
Example:
the determinative (or determinant) battle
Synonyms:
deciding; determinant; determinative; determining
Classified under:
Similar:
decisive (determining or having the power to determine an outcome)
Derivation:
determinant (a determining or causal element or factor)
determine (reach, make, or come to a decision about something)
determine (decide upon or fix definitely)
Context examples:
It is concerned with integrated approaches for the prevention and management of chronic disease-in-general (DIG) or the common determinants of chronic disease.
(Lifestyle and Disease Prevention, NCI Thesaurus)
A cell-based vaccine composed of allogeneic dendritic cells (DC), pulsed with patient-specific non-Hodgkin's lymphoma idiotype (Id) determinants conjugated to keyhole limpet hemocyanin (KLH), with potential antitumor activity.
(Dendritic Cell-Idiotype-Keyhole Limpet Hemocyanin Vaccine, NCI Thesaurus)
The Division of Cancer Epidemiology and Genetics (DCEG) is the primary focus within the National Cancer Institute for population based research on environmental and genetics determinants of cancer.
(Division of Cancer Epidemiology and Genetics, NCI Thesaurus)
A synthetic antibody produced by a genetically homogenous population of hybrid cells (hybridoma) against determinant idiotypes (Id) which usually mimic human epitopes.
(Anti-Idiotype Specified Monoclonal Antibody, NCI Thesaurus)
Local surface sites on antibodies which react with antigen determinant sites on antigens.
(Antibody Binding Site, NLM, Medical Subject Headings)
A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells.
(Apolizumab, NCI Thesaurus)
The CYP2A6 wild-type allele is both a determinant of smoking behavior and a susceptibility factor for lung cancer.
(CYP2A6 wt Allele, NCI Thesaurus)
An antibody directed against the individual antigenic determinants (idiotopes) on the variable region of an immunoglobulin molecule.
(Anti-Idiotype Antibody, NCI Thesaurus)
Amplification of the ABCB1 gene is a major determinant in the development of multi-drug resistance, which decreases the effectiveness of many chemotherapeutic agents used in cancer treatment.
(ABCB1 wt Allele, NCI Thesaurus)
Amplification of the ABCB1 gene is a major determinant in the development of multi-drug resistance which decreases the effectiveness of many chemotherapeutic agents used in cancer treatment.
(ABCB1 1 Allele, NCI Thesaurus)
