Library / English Dictionary

    DISRUPTED

    Pronunciation (US): Play  (GB): Play

     I. (adjective) 

    Sense 1

    Meaning:

    Marked by breaks or gapsplay

    Example:

    many routes are unsafe or disrupted

    Classified under:

    Adjectives

    Similar:

    discontinuous; noncontinuous (not continuing without interruption in time or space)

     II. (verb) 

    Sense 1

    Past simple / past participle of the verb disrupt

    Credits

     Context examples: 

    Oligomers are the main form of Hsp27 with molecular chaperone activity and are disrupted by phosphorylation of Hsp27 to form dimers and monomers.

    (HSP27 Regulation Pathway, NCI Thesaurus/BIOCARTA)

    This allele, which encodes disrupted in renal carcinoma 3 transcript, may play a role in renal cell carcinoma.

    (DIRC3 wt Allele, NCI Thesaurus)

    By inactivating UL39, viral ribonucleotide reductase activity is disrupted, resulting in the inhibition of nucleotide metabolism and viral DNA synthesis in nondividing cells but not in dividing cells.

    (G207, NCI Thesaurus)

    Additional symptoms may include emotional changes and disrupted sleep.

    (Immune system may mount an attack in Parkinson’s disease, National Institutes of Health)

    The findings from this study highlight the relevance of energetics for ensuring normal brain function and reveal how it is disrupted by excessive alcohol consumption.

    (Study of brain energy patterns provides new insights into alcohol effects, National Institutes of Health)

    Underlying such impaired neuronal growth and function, the researchers discovered that the mutant SETD1A gene disrupted regulation of many other genes with which it is networked.

    (Schizophrenia risk gene linked to cognitive deficits in mice, National Institutes of Health)

    The dorms without AC were louder at night because of fan and street noise, which could have disrupted sleep.

    (Hot Dorm Rooms Could Affect Students' Memory, Sadie Witkowski/VOA)

    François was surprised, too, when they shot out in a tangle from the disrupted nest and he divined the cause of the trouble.

    (The Call of the Wild, by Jack London)

    Compared to genes, proteins have been relatively understudied in human blood, even though they are the ‘effectors’ of human biology, are disrupted in many diseases, and are the targets of most medicines.

    (Scientists create ‘genetic atlas’ of proteins in human blood, University of Cambridge)

    The researchers used two types of mice in their investigation: one normal, the other with dopamine signaling disrupted.

    (Neurons That Control Brain's Body Clock Identified, The Titi Tudorancea Bulletin)


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