| Library / English Dictionary |
DISSOCIATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The act of removing from association
Classified under:
Nouns denoting acts or actions
Hypernyms ("dissociation" is a kind of...):
separation (the act of dividing or disconnecting)
Derivation:
dissociate (regard as unconnected)
dissociate (part; cease or break association with)
Sense 2
Meaning:
(chemistry) the temporary or reversible process in which a molecule or ion is broken down into smaller molecules or ions
Classified under:
Nouns denoting natural processes
Hypernyms ("dissociation" is a kind of...):
chemical action; chemical change; chemical process ((chemistry) any process determined by the atomic and molecular composition and structure of the substances involved)
Domain category:
chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)
Derivation:
dissociate (to undergo a reversible or temporary breakdown of a molecule into simpler molecules or atoms)
Sense 3
Meaning:
A state in which some integrated part of a person's life becomes separated from the rest of the personality and functions independently
Synonyms:
disassociation; dissociation
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("dissociation" is a kind of...):
mental condition; mental state; psychological condition; psychological state ((psychology) a mental condition in which the qualities of a state are relatively constant even though the state itself may be dynamic)
Hyponyms (each of the following is a kind of "dissociation"):
compartmentalisation; compartmentalization (a mild state of dissociation)
dissociative disorder (dissociation so severe that the usually integrated functions of consciousness and perception of self break down)
Derivation:
dissociate (regard as unconnected)
dissociate (part; cease or break association with)
Context examples:
BTAF1 inhibits TBP-driven RNA polymerase II and III transcription by driving the dissociation of TBP from DNA and freeing the TBP to associate with other TATA boxes or TATA-less promoters.
(B-TFIID Subunit Gene, NCI Thesaurus)
The strength of noncovalent chemical binding between two substances as measured by the dissociation constant of the complex.
(Affinity, NCI Thesaurus)
Clinical signs include limitation of upward gaze, light-near dissociation of the pupillary response, eyelid retraction (Collier's sign) and convergence-retraction nystagmus.
(Parinaud Syndrome, NCI Thesaurus)
Once they bind retinoic acid a conformational change in the receptors cause the dissociation of the corepressors and the binding of coactivators with histone acetylase activity.
(Chromatin Remodeling Complex and Coactivator Pathway, NCI Thesaurus/BIOCARTA)
It prevents dissociation of IRAK and IRAK4 from MYD88 and formation of IRAK/TRAF6 complexes.
(Interleukin-1 Receptor-Associated Kinase 3, NCI Thesaurus)
D4-GDP dissociation inhibitor (D4-GDI) is a negative regulator of the ras related Rho Family of GTPases.
(D4-GDI Signaling Pathway, NCI Thesaurus/BIOCARTA)
It secretes bicarbonate made in the cell by the dissociation of carbonic acid in the presence of carbonic anhydrase II.
(Pancreatic Centroacinar Cell, NCI Thesaurus)
The affected pupil will respond more briskly to accommodation than to light (light-near dissociation) and is supersensitive to dilute pilocarpine eye drops, which induce pupillary constriction.
(Holmes-Adie Syndrome, NLM, Medical Subject Headings)
Through physical or functional dissociation, Enzyme Uncoupling involves alteration (typically disruption) of activity of a physically or functionally coordinated biological complex that possesses catalytic activity.
(Enzyme Uncoupling, NCI Thesaurus)
Cytokine-activated serine phosphorylation of IKBs by IKBKA/IKBKB disables the NFKB inhibition by dissociation; promotes polyubiquitinated proteasome-dependent IKB degradation; and allows NFKB nuclear translocation, binding at kappa-B DNA motifs, and target gene transcription.
(I Kappa B, NCI Thesaurus)
