| Health / Medical Topics |
DNA Binding Protein
Definition 1
Proteins that non-covalently interact with deoxyribonucleic acid as a result of intermolecular physical forces and spatial complementarity. Many genetic regulatory DNA binding proteins bind to double- or single-stranded DNA in a sequence-specific manner and share common structural motifs such as the zinc-finger, helix-turn-helix, and leucine zipper. (NCI Thesaurus)
Definition 2
Proteins which bind to DNA. The family includes proteins which bind to both double- and single-stranded DNA and also includes specific DNA binding proteins in serum which can be used as markers for malignant diseases. (NLM, Medical Subject Headings)
YOU MAY ALSO LIKE
A region of a protein that interacts with DNA. Among the various recognized structural motifs present in DNA binding domains are the…
DNA binding molecules regulate mechanisms central to cellular function, including DNA replication and gene expression. Many small molecules that mimic or block…
Used in reference to proteins or low molecular weight solutes (ligands) that interact specifically with DNA, in either a DNA-sequence dependent or…
Any DNA based laboratory tests.
DNA Alkylation involves the addition of alkyl groups to any of several vulnerable positions on all four of the DNA bases. Alkylating…
DNA Adduction involves formation of a covalent bond between a molecule and the DNA macromolecule.
