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DNA Ligase
A family of enzymes that catalyze the formation of phosphodiester bonds to repair broken strands of DNA. (NCI Thesaurus)
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A collection of DNA molecules that have been cloned in vectors.
DNA Intrastrand Crosslinking involves the formation of a covalent bond between two bases on the same DNA strand.
DNA Interstrand Crosslinking involves the formation of a covalent bond between two bases on different DNA strand.
DNA interstrand cross-links (ICLs) are very toxic to dividing cells, because they induce mutations, chromosomal rearrangements and cell death. A number of…
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DNA Intercalation involves insertion by covalent linkage of a molecule into the double-stranded deoxyribonucleotide polymer between the internal purine and pyrimidine base…
