Health / Medical Topics

    DNase-I Footprinting

    A DNA footprinting method which is commonly used for analyzing specific protein-DNA interactions. In this technique, a restriction fragment containing a specific binding site is labeled at one end and digested with DNAseI. The result is a ladder of bands, representing the various sites at which DNase I cuts. The distribution of radioactivity is visualized by autoradiography. (NCI Thesaurus)




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