Health / Medical Topics

    DRD2 wt Allele

    Human DRD2 wild-type allele is located within 11q23 and is approximately 66 kb in length. This allele, which encodes D(2) dopamine receptor protein, plays a role in the inhibition of adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia and allelic variant mutants are associated with schizophrenia. (NCI Thesaurus)




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