Library / English Dictionary

    ENDOTHELIUM

    Pronunciation (US): Play  (GB): Play

    Irregular inflected form: endothelia  Listen to US pronunciation  Listen to GB pronunciation

     I. (noun) 

    Sense 1

    Meaning:

    An epithelium of mesoblastic origin; a thin layer of flattened cells that lines the inside of some body cavitiesplay

    Classified under:

    Nouns denoting body parts

    Hypernyms ("endothelium" is a kind of...):

    epithelial tissue; epithelium (membranous tissue covering internal organs and other internal surfaces of the body)

    Derivation:

    endothelial (of or relating to or located in the endothelium)

    Credits

     Context examples: 

    Vascular NO (endothelia) inhibits muscle contraction through a cGMP pathway, inhibits platelet aggregation, and mediates VEGF-induced angiogenesis.

    (Nitric Oxide Synthetase, NCI Thesaurus)

    Upon administration, GMI-1070 prevents the interaction between leukocytes and the endothelium and may prevent cell activation and adhesion.

    (Pan-Selectin Antagonist GMI-1070, NCI Thesaurus)

    The colored disc of the eye composed of connective tissue, epithelium, and endothelium.

    (Iris, NCI Thesaurus)

    MoAb muJ591 recognizes the extracellular domain of the prostate-specific membrane antigen (PSMA) and reacts with tumor vascular endothelium.

    (Iodine I 131 Monoclonal Antibody muJ591, NCI Thesaurus)

    A rare malignant soft tissue neoplasm arising from the vascular endothelium of the adrenal gland.

    (Adrenal Gland Angiosarcoma, NCI Thesaurus)

    It is released by the vascular endothelium and mediates the relaxation induced by some vasodilators such as acetylcholine and bradykinin.

    (Nitric Oxide, NLM, Medical Subject Headings)

    The expression of DLL4 is highly restricted to the vascular endothelium; DLL4/Notch signaling is required for the development of functional tumor blood vessels.

    (Anti-DLL4 Monoclonal Antibody MEDI0639, NCI Thesaurus)

    During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (CAM) and then migrate across the vascular endothelium.

    (Leukocyte Transendothelial Migration Pathway, NCI Thesaurus/KEGG)

    The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous epithelium, Bowman's membrane, stroma, Descemet's membrane, and mesenchymal endothelium.

    (Murine Cornea, NCI Thesaurus)

    Pentoxifylline inhibits phosphodiesterase, resulting in increased levels of cyclic adenosine monophosphate (cAMP) in erythrocytes, endothelium, and the surrounding tissues.

    (Pentoxifylline, NCI Thesaurus)


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