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EX VIVO
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of a biological process occurring in an artificial environment outside the living organism
Example:
in vitro fertilization
Synonyms:
Classified under:
II. (adverb)
Sense 1
Meaning:
In an artificial environment outside the living organism
Example:
an egg fertilized in vitro
Synonyms:
ex vivo; in vitro
Classified under:
Context examples:
A tumor-targeted therapy consisting of cytotoxic T lymphocytes (CTLs) that are exposed ex vivo to dendritic cells (DCs) transfected with a recombinant adeno-associated virus (rAAV) encoding a specific tumor associated antigen (TAA) gene.
(AAV-DC-CTL Tumor Cell Targeting Therapy, NCI Thesaurus)
T cells directed against HER2, overexpressed on many tumor cells, are collected from HER2-expressing tumor tissue, expanded ex vivo and, then re-introduced in the patient.
(Ex Vivo-Expanded HER2-Specific T Cells, NCI Thesaurus)
A dendritic cell (DC) vaccine containing ex vivo expanded autologous DCs obtained from a patient with leukemia with potential immunostimulating activity.
(Host Dendritic Cell Vaccine-001 MSSM/BIIR, NCI Thesaurus)
Allogeneic human autologous HSCs are isolated and transduced ex vivo with three different anti-HIV genes.
(Gene-Modified HIV-Protected Hematopoietic Stem Cells, NCI Thesaurus)
An umbilical cord blood product that has been expanded ex vivo and can be used during single umbilical cord blood transplantation.
(Expanded Umbilical Cord Blood Product HSC835, NCI Thesaurus)
Ex vivo, the lymphocytes are activated against EBV-specific antigens and then returned to the patient, where they mount a specific immune response against EBV-positive tumor cells.
(Autologous Epstein-Barr Virus-Specific Cytotoxic T Lymphocytes, NCI Thesaurus)
Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
(Murine Lymphocytes, Tumor-Infiltrating, NCI Thesaurus)
Upon isolation, transduction, expansion ex vivo, and reintroduction into the patient, the NY-ESO-1 reactive TCR-transduced autologous PBLs bind to NY-ESO-1-overexpressing tumor cells.
(NY-ESO-1 Reactive TCR Retroviral Vector Transduced Autologous PBL, NCI Thesaurus)
The modified T lymphocytes are cloned using an ex vivo technique and infused back into the patient, where they may elicit a host immune response against tumor cells.
(PG13/LNc8 Retroviral Transduced Cloned T-Cells, NCI Thesaurus)
CD8+ T-lymphocytes are exposed ex vivo to autologous dendritic cells (DCs) pulsed with MART-1 antigen peptide and grown in the presence of IL-21.
(Autologous IL-21-Modulated CD8+ MART1-Specific T Cells, NCI Thesaurus)
