Health / Medical Topics

    FANCB wt Allele

    Human FANCB wild-type allele is located in the vicinity of Xp22.2 and is approximately 30 kb in length. This allele, which encodes Fanconi anemia group B protein, may be involved in the modulation of both protein ubiquitination and DNA repair. Mutation of the gene is associated with Fanconi anemia. (NCI Thesaurus)




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