FANCM wt Allele

Human FANCM wild-type allele is located in the vicinity of 14q21.3 and is approximately 65 kb in length. This allele, which encodes Fanconi anemia group M protein, is involved in a specific protein ubiquination that is necessary for DNA repair. Cytogenetic aberrations in the FANCM gene are both a cause of Fanconi anemia and a predisposing factor in the development of malignancies. (NCI Thesaurus)

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FANCM Gene

This gene plays a role in transcriptional regulation and ubiquitination.

FANCL wt Allele

Human FANCL wild-type allele is located in the vicinity of 2p16.1 and is approximately 82 kb in length. This allele, which encodes…

FANCL Gene

This gene is involved in the mediation of protein ubiquitination.

FANCI wt Allele

Human FANCI wild-type allele is located in the vicinity of 15q26.1 and is approximately 73 kb in length. This allele, which encodes…

FANCI Gene

This gene plays a role in the mediation of DNA repair.

FANCG wt Allele

Human FANCG wild-type allele is located within 9p13 and is approximately 6 kb in length. This allele, which encodes fanconi anemia group…