Health / Medical Topics

    FBXW4 wt Allele

    Human FBXW4 wild-type allele is located in the vicinity of 10q24 and is approximately 85 kb in length. This allele, which encodes F-box/WD repeat-containing protein 4, is involved in the mediation of both limb morphogenesis and protein catabolism. Mutations in the gene are associated with split-hand/foot malformation type 3. (NCI Thesaurus)




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