| Library / English Dictionary |
FEEDBACK
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Response to an inquiry or experiment
Classified under:
Nouns denoting communicative processes and contents
Hypernyms ("feedback" is a kind of...):
answer; reply; response (a statement (either spoken or written) that is made to reply to a question or request or criticism or accusation)
Derivation:
feed back (respond to a query or outcome)
Sense 2
Meaning:
The process in which part of the output of a system is returned to its input in order to regulate its further output
Classified under:
Nouns denoting natural processes
Hypernyms ("feedback" is a kind of...):
action; activity; natural action; natural process (a process existing in or produced by nature (rather than by the intent of human beings))
Hyponyms (each of the following is a kind of "feedback"):
negative feedback (feedback in opposite phase with (decreasing) the input)
positive feedback; regeneration (feedback in phase with (augmenting) the input)
Derivation:
feed back (submit (information) again to a program or automatic system)
Context examples:
By inhibiting mTOR to a lesser extent than PI3K, PQR309 does not interfere with the mTOR-mediated negative feedback loop on PI3K signaling.
(pan-PI3K/mTOR Inhibitor PQR309, NCI Thesaurus)
This pathway illustrates two of the cofactor regulatory factors, MEF2 and PPARa, and an example orphan receptor feedback inhibition loop.
(PGC1a Regulation Pathway, NCI Thesaurus/BIOCARTA)
Formin-dependent activation of BMP-antagonist Gremlin induces FGF4 and the SHH/FGF4 feedback loop.
(Oncogene HST, NCI Thesaurus)
As part of a feedback loop, PKA can inhibit the activation of particulate guanylyl cyclase.
(Olfactory Transduction Pathway, NCI Thesaurus/KEGG)
Together, these lead to decreased IGF-I receptor activation and a decreased feedback to the hypothalamus and pituitary.
(Food Intake and Energy Homeostasis Pathway, NCI Thesaurus/BIOCARTA)
Mimicking the negative feedback mechanism of testosterone, nandrolone decanoate also suppresses the secretion of luteinizing hormone (LH).
(Nandrolone Decanoate, NCI Thesaurus)
BCR ligation stimulates a transient induction of MYC that leads to high level CTCF expression and feedback suppression of MYC transcription.
(CTCF Pathway, NCI Thesaurus/BIOCARTA)
Alteration of positive or negative feedback mechanisms can induce hormone release.
(Endocrine Secretory Process, NCI Thesaurus)
In the nucleus, Per and Cry form a feedback loop that inhibits transcriptional activation by Bmal1 and Clock, lowering their own expression in the process.
(Circadian Rhythm Pathway BioCarta, NCI Thesaurus/BIOCARTA)
This also removes the inhibition of PKA by DARPP-32, forming a positive feedback loop for further DARPP-32 inactivation by PKA.
(CK1/CDK5 Regulation Pathway, NCI Thesaurus/BIOCARTA)
