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FOLLICLE-STIMULATING HORMONE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A gonadotropic hormone that is secreted by the anterior pituitary and stimulates growth of Graafian follicles in female mammals, and activates the cells in male mammals that form sperm
Synonyms:
follicle-stimulating hormone; FSH
Classified under:
Hypernyms ("follicle-stimulating hormone" is a kind of...):
gonadotrophic hormone; gonadotrophin; gonadotropic hormone; gonadotropin (hormone secreted by the anterior pituitary gland and placenta; stimulates the gonads and controls reproductive activity)
Context examples:
GnRH causes the pituitary gland to make luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
(GnRH, NCI Dictionary)
A basophilic cell of the anterior pituitary gland whose granules secrete follicle-stimulating hormone
(FSH Cell, NCI Thesaurus)
Upon administration of GTx-758, this agent suppresses the secretion of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the pituitary gland through feedback inhibition.
(Estrogen Receptor Agonist GTx-758, NCI Thesaurus)
A process that involves the binding of any member of the group of pituitary hormones, including growth hormone, thyroid stimulating hormone, adrenocorticotropic hormone, follicle-stimulating hormone, luteinizing hormone and prolactin, to their respective receptors.
(Pituitary Hormone Receptor Binding, NCI Thesaurus)
As a selective estrogen receptor modulator (SERM), enclomiphene binds to hypothalamic estrogen receptors, blocking the negative feedback of endogenous estrogens and stimulating the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus; released GnRH subsequently stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary, resulting in ovulation.
(Enclomiphene Citrate, NCI Thesaurus)
G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor.
(G Protein-Coupled Receptor, NCI Thesaurus)
