| Health / Medical Topics |
Frameshift Mutation Abnormality
Insertion or deletion of one, two or four nucleotides that alters the correct reading frame of an amino acid-coding DNA sequence, resulting in an amino acid sequence that is changed or truncated. Frame shift mutations typically result in a mutated protein product that is inactive. This type of mutation abnormality can be either inherited or somatic. (NCI Thesaurus)
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