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FREE RADICAL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An atom or group of atoms with at least one unpaired electron; in the body it is usually an oxygen molecule that has lost an electron and will stabilize itself by stealing an electron from a nearby molecule
Example:
in the body free radicals are high-energy particles that ricochet wildly and damage cells
Synonyms:
Classified under:
Hypernyms ("free radical" is a kind of...):
atom ((physics and chemistry) the smallest component of an element having the chemical properties of the element)
Context examples:
An oxygen radical is a free radical.
(Oxygen radical, NCI Dictionary)
In addition, OKN007 may induce changes in tumor metabolism and scavenge free radicals.
(PBN Derivative OKN-007, NCI Thesaurus)
In addition, mesalamine may act as a scavenger of reactive oxygen free radicals.
(Olsalazine, NCI Thesaurus)
They also inhibit a variety of pro-inflammatory enzymes, such as cyclooxygenase 1 (COX-1) and COX-2, block the formation of reactive-oxygen species and neutralize free radicals.
(Olive Oil Extract/Curcumin-based Capsule, NCI Thesaurus)
These genes help protect the cell from damage caused by free radicals (unstable molecules made during normal cell metabolism).
(NFE2L2, NCI Dictionary)
As an oxygen mimetic, nimorazole induces free radical formation and is able to sensitize hypoxic cells to the cytotoxic effects of ionizing radiation.
(Nimorazole, NCI Thesaurus)
Treatment with antioxidants in order to protect cells against damage caused by oxygen-free radicals.
(Antioxidants Therapy, NCI Thesaurus)
This agent may both prevent the formation of free radicals and neutralize free radicals.
(Curcumin C3 Complex, NCI Thesaurus)
Antioxidants bind to and neutralize ('scavenge') free radicals, thereby transforming them into non-toxic compounds and blocking their genotoxic and carcinogenic effects.
(Antioxidant, NCI Thesaurus)
Within mitochondria, mutant SOD1 may interfere with the anti-apoptotic function of Bcl-2, affect mitochondrial import by interfering with the translocation machinery (TOM/TIM), and generate toxic free radicals (ROS) via aberrant superoxide chemistry.
(Amyotrophic Lateral Sclerosis Pathway, NCI Thesaurus/KEGG)
