Health / Medical Topics

    Fuhrman Nuclear Grade

    A 4-point scale for renal cell carcinoma that indicates the level of protein synthesis activity in malignant cells based on the appearance of the nuclei. The grading ranges from I (best prognosis) to IV (worst prognosis). (NCI Thesaurus)




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    Nuclei bizarre and multilobated, 20 microns or greater, nucleoli prominent, chromatin clumped.
    Nuclei very irregular, approximately 20 microns; nucleoli large and prominent.
    Nuclei slightly irregular, approximately 15 microns; nucleoli evident.
    Nuclei round, uniform, approximately 10 microns; nucleoli inconspicuous or absent
    Belongs to the family of EC 2.4.1 glycosyltransferases. The enzyme catalyzes the transfer of a fucose molecule from a dinucleotide compound to…
    An autosomal recessive lysosomal storage disease characterized by a defective alpha-L-fucosidase. It results in accumulation of fucose in the tissues. Signs and…

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