Health / Medical Topics

    G Protein Pathway Suppressor 1 Protein

    Definition 1

    Encoded by human GPS1 Gene, 471-aa 53-kDa G Protein Pathway Suppressor 1 Protein contains a PCI domain and has similarity to signal transduction regulator FUS6 (Arabidopsis). GPS1 suppresses G-protein- and MAP kinase-mediated signal transduction. (NCI Thesaurus)

    Definition 2

    G Protein Pathway Suppressor 1 Protein, encoded by the GPS1 gene, shares significant similarity with Arabidopsis FUS6, a regulator of light-mediated signal transduction in plant cells. The GPS1 gene is known to suppress G-protein and mitogen-activated protein kinase-mediated signal transduction in mammalian cells. (NCI Thesaurus/LocusLink)




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