Health / Medical Topics

    GATA4 wt Allele

    Human GATA4 wild-type allele is located within 8p23.1-p22 and is approximately 56 kb in length. This allele, which encodes transcription factor GATA-4 protein, plays a role in the modulation of both transcription and cardiovascular development. Mutation of the gene is associated with atrial septal defect type 2. (NCI Thesaurus)




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