Health / Medical Topics

    Gene Signature

    A form of gene expression profiling that is indicative of the biological behavior of a tumor or cancer. This pattern of expression is comprised of unique clusters of genes that display differential levels of expression. The technology is based on microarray analysis and allows for accurate prognostication based upon these criteria. (NCI Thesaurus)




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    The location of a feature (for example a SNP, repeat, etc.) relative to the coding sequence of a gene.
    Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene expression at the level of…
    Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal…
    A variation in the amino acid sequence of a specific gene product.
    A protein, RNA or a complex that contains proteins and/or RNA.
    The physical location of a gene expressed as chromosome and start and end base positions.

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