| Health / Medical Topics |
Genomic Instability
A biological process consisting of chromosomal rearrangements and duplications. These phenotypes are often seen in the karyotype of cancer cells, where there is an imbalance between the mechanisms of cell-cycle control and mutation rates within aberrant genes. Ataxia telangiectasia is a disease that is resultant from mutations in the ATM gene, which is a cell cycle checkpoint gene. Nijmegen breakage syndrome is also a disease characterized by chromosomal and genomic instability. (NCI Thesaurus)
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Parent-specific expression or repression of genes or chromosomes in offspring.
One or more characters and/or numbers that are used to identify, name, or characterize the nature, properties, or contents of genomic sequences,…
The physical location on a specified chromosome of a feature or area of interest expressed as a base pair position.
The DNA that is part of the normal chromosomal complement of an organism.
A laboratory method that is used to learn about all the genes in a person or in a specific cell type, and…
A measurable DNA or RNA characteristic that is an indicator of normal biologic processes, pathogenic processes, and/or response to therapeutic or other…
