GLI3 wt Allele

Human GLI3 wild-type allele is located in the vicinity of 7p13 and is approximately 272 kb in length. This allele, which encodes zinc finger protein GLI3, plays a role in the regulation of sonic hedgehog-dependent transcription of specific genes during the development of multiple organ systems. This gene is the site of a mutation that is linked to Greig cephalopolysyndactyly syndrome. (NCI Thesaurus)

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GLI3 Gene

This gene plays a regulatory role in limb development and is involved in sonic hedgehog signal transduction.

GLI2 wt Allele

Human GLI2 wild-type allele is located in the vicinity of 2q14 and is approximately 200 kb in length. This allele, which encodes…

GLI2 Gene

This gene is involved in transcriptional regulation and plays a role in sonic hedgehog signal transduction.

GLI1 wt Allele

Human GLI1 wild-type allele is located within 12q13.2-q13.3 and is approximately 12 kb in length. This allele, which encodes zinc finger protein…

GLI1 Gene

This gene plays a regulatory role in transcription and embryonic development.

GLI Family Protein

A group of DNA-binding proteins that contain zinc finger repeats and involves pattern formation process.