Glucuronic acid

Pronunciation

Definition 1

A form of a type of sugar called glucose that helps remove harmful substances from the body. Glucuronic acid and the harmful substance combine in the liver and then are passed in the urine. Glucuronic acid is also found in other substances in the body, such as cartilage and synovial fluid (fluid found in the joints). (NCI Dictionary)

Definition 2

A carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids involves glucuronidation, a process in which water-soluble, excretable glucuronides of these substances are formed via glycosidic linkages to glucuronic acid. UDP-glucuronic acid, formed in the liver through the linkage of glucuronic acid to uridine diphosphate (UDP) via a glycosidic bond, is an intermediate in the process of glucuronidation. (NCI Thesaurus)

YOU MAY ALSO LIKE

Glucosylceramidase

Glucosylceramidase (536 aa, ~60 kDa) is encoded by the human GBA gene. This protein is involved in glycolipid metabolism.

Glucosulfone Sodium

A sodium salt form of glucosulfone, an agent used to treat mycobacterial infections.

Glucosulfone Free Acid

A sulfone drug that is converted to dapsone in the body. It has been used to treat mycobacterial infections, including tuberculosis and…

Glucosinolate

A class of organic compounds that are derived from a glucose that has been modified by an amino acid. These compounds are…

Glucosidase Inhibitor

Any substance that inhibits glucosidase, specifically alpha-glucosidase in the brush border of the small intestines, an enzyme that catalyzes the breakdown of…

Glucose-6-Phosphate Isomerase

Glucose-6-phosphate isomerase (558 aa, ~63 kDa) is encoded by the human GPI gene. This protein is involved in glycolysis in as a…