| Library / English Dictionary |
GLYCOL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of a class of alcohols having 2 hydroxyl groups in each molecule
Synonyms:
dihydric alcohol; diol; glycol
Classified under:
Hypernyms ("glycol" is a kind of...):
alcohol (any of a series of volatile hydroxyl compounds that are made from hydrocarbons by distillation)
Sense 2
Meaning:
A sweet but poisonous syrupy liquid used as an antifreeze and solvent
Synonyms:
ethanediol; ethylene glycol; glycol
Classified under:
Nouns denoting substances
Hypernyms ("glycol" is a kind of...):
antifreeze (a liquid added to the water in a cooling system to lower its freezing point)
Context examples:
A formulation of polyethylene glycol (PEG)-modified liposomes encapsulating the semisynthetic derivative of camptothecin irinotecan, with antineoplastic activity.
(Pegylated Liposomal Irinotecan, NCI Thesaurus)
The propylene glycol form of cefatrizine, a semi-synthetic, first-generation cephalosporin with strong activity against gram-positive cocci except enterococci.
(Cefatrizine Propylene Glycolate, NCI Thesaurus)
A Fab fragment of a recombinant, humanized monoclonal antibody directed against the proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) and conjugated to polyethylene glycol (PEG), with anti-inflammatory activity.
(Certolizumab Pegol, NCI Thesaurus)
A covalent conjugate of recombinant interferon alpha and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent.
(Pegylated Interferon Alfa, NCI Thesaurus)
A covalent conjugate of recombinant interferon alfa, subtype 2a, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent.
(Peginterferon alfa-2a, NCI Thesaurus)
A formulation of polyethylene glycol (PEG)-encapsulated irinotecan with antineoplastic activity.
(Pegylated Irinotecan, NCI Thesaurus)
A proprietary 44-nucleotide L-stereoisomer RNA oligonucleotide conjugated to a 40 kDa polyethylene glycol (PEG) that targets hepcidin with potential anti-anemic activity.
(PEG-linked L-RNA Oligonucleotide Hepcidin-targeting Agent NOX-H94, NCI Thesaurus)
The sodium salt form of pegaptanib, a 28-mer RNA aptamer covalently linked to two branched 20-kD polyethylene glycol (PEG) chains, with anti-angiogenic activity.
(Pegaptanib Sodium, NCI Thesaurus)
A covalent conjugate of recombinant interferon alpha, subtype 2b, and polyethylene glycol (PEG), used as an antiviral and antineoplastic agent.
(Peginterferon alfa-2b, NCI Thesaurus)
Conjugation of the cytokine with a branched polyethylene glycol molecule (pegylation) significantly increases its therapeutic half-life.
(Pegfilgrastim, NCI Thesaurus)
