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GONADAL
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to the gonads
Example:
gonadal hormones
Classified under:
Relational adjectives (pertainyms)
Pertainym:
gonad (a gland in which gametes (sex cells) are produced)
Derivation:
gonad (a gland in which gametes (sex cells) are produced)
Context examples:
A technique for transplantation of stem cells, derived from embryonic gonadal ridge (embryonic germ cells), which are pluripotent and capable of self-renewal for long periods.
(Male Gonadal Ridge Implantation, NCI Thesaurus)
It is often associated with gonadal dysgenesis and abnormal karyotype.
(Gonadoblastoma, NCI Thesaurus)
Gonadal dysgenesis is usually part of a genetic syndrome.
(Gonadal dysgenesis, NCI Dictionary)
A congenital disorder characterized by the complete absence of gonadal tissue.
(Gonadal Agenesis, NCI Thesaurus)
Point mutations of the gene are associated with gonadal dysgenesis.
(CBX2 wt Allele, NCI Thesaurus)
Prolonged administration of buserelin results in sustained inhibition of gonadotropin production, suppression of testicular and ovarian steroidogenesis, and reduced levels of circulating gonadotropin and gonadal steroids.
(Buserelin, NCI Thesaurus)
The drugs mechlorethamine and vincristine from the MOPP regimen have been replaced with chlorambucil and vinblastine to minimize gonadal and neurological toxicity, respectively.
(chlVPP Regimen, NCI Thesaurus)
Representative examples include gonadal agenesis, dysgenesis, and hypogonadism.
(Non-Neoplastic Gonadal Disorder, NCI Thesaurus)
A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.
(Diethylstilbestrol, NCI Thesaurus)
Human EG cells are derived from the primordial germ cells, which occurs in a specific part of the embryo/fetus called the gonadal ridge, and which normally develop into mature gametes (eggs and sperm).
(EG Cell Line, NCI Thesaurus)
