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GP
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A physician who is not a specialist but treats all illnesses
Synonyms:
Classified under:
Hypernyms ("GP" is a kind of...):
doc; doctor; Dr.; MD; medico; physician (a licensed medical practitioner)
Hyponyms (each of the following is a kind of "GP"):
country doctor (a doctor who practices in the country (rather than in a city) usually remote from a modern hospital)
family doctor (a general practitioner who treats all the family members)
Context examples:
In addition, this agent is a not a substrate of the P-glycoprotein (P-gp), a multidrug resistance pump often overexpressed in cancer cells.
(Iso-fludelone, NCI Thesaurus)
Biricodar binds directly to the plasma membrane drug-efflux pumps P-glycoprotein (P-gp) and multidrug resistance protein 1 (MRP-1) and inhibits their activities, which may result in increased intracellular accumulation and retention of cytotoxic agents.
(Biricodar Dicitrate, NCI Thesaurus)
Researchers say the simple test for the neurodegenerative disease, which has been found to be more than 90 per cent accurate, could be available at GP surgeries “within a few years”.
(New Alzheimer’s Blood Test Could Detect Signs of Symptoms Decades Earlier, The Titi Tudorancea Bulletin)
In addition, epothilone KOS-1584 is a poor substrate for the P-glycoprotein (P-gp) drug efflux pump.
(Epothilone KOS-1584, NCI Thesaurus)
The results provided evidence of multiple mechanisms by which the antibodies inhibit actions of all forms of GP, thus preventing infection by halting viral entry into the host cell.
(Broadly acting antibodies found in plasma of Ebola survivors, National Institutes of Health)
An orally bioavailable combination tablet containing the semisynthetic camptothecin derivative irinotecan and the multidrug resistance (MDR) efflux pump P-glycoprotein (P-gp) inhibitor HM30181AK, with potential antineoplastic activity.
(Irinotecan/P-glycoprotein Inhibitor HM30181AK Combination Tablet, NCI Thesaurus)
Twelve months after diagnosis, patients assessed their GP’s empathy and their experiences of diabetes care over the preceding year using the consultation and relational empathy (CARE) questionnaire.
(Patients with an ‘empathic’ GP at reduced risk of early death, University of Cambridge)
Dofequidar fumarate, like many other MDR reversal agents, binds competitively to the drug-binding site of the transmembrane P-glycoprotein efflux pump (P-gp).
(Dofequidar Fumarate, NCI Thesaurus)
A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation.
(Abciximab, NCI Thesaurus)
This agent circumvents multidrug-resistance (MDR) transporters, including P-glycoprotein (P-gp).
(Annamycin Liposomal, NCI Thesaurus)
