| Health / Medical Topics |
Growth Differentiation Factor 5
Growth Differentiation Factor 5, encoded by the human GDF5 gene, is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This protein is predominantly expressed in long bones during human embryonic development. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. (From LocusLink, Swiss-Prot and NCI) (NCI Thesaurus)
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