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HDL
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A lipoprotein that transports cholesterol in the blood; composed of a high proportion of protein and relatively little cholesterol; high levels are thought to be associated with decreased risk of coronary heart disease and atherosclerosis
Synonyms:
alpha-lipoprotein; HDL; high-density lipoprotein
Classified under:
Hypernyms ("HDL" is a kind of...):
lipoprotein (a conjugated protein having a lipid component; the principal means for transporting lipids in the blood)
Meronyms (substance of "HDL"):
HDL cholesterol (the cholesterol in high-density lipoproteins; the 'good' cholesterol; a high level in the blood is thought to lower the risk of coronary artery disease)
Context examples:
A measurement of the high-density lipoprotein (HDL) cholesterol subclass 2 in a biological specimen.
(HDL-Cholesterol Subclass 2 Measurement, NCI Thesaurus/CDISC)
A relative measurement (ratio or percentage) of the amount of HDL cholesterol compared to LDL cholesterol in a biological specimen.
(HDL Cholesterol to LDL Cholesterol Ratio Measurement, NCI Thesaurus/CDISC)
The work demonstrates that the protective effects of HDL are more dependent upon how it functions than merely how much of it is present.
(When HDL cholesterol doesn’t protect against heart disease, NIH)
An agonist of niacin receptors capable of mimicking niacin's ability to increase high-density lipoprotein (HDL).
(Acifran, NCI Thesaurus)
The data included measurements of each participant's LDL cholesterol, high-density lipoprotein (HDL) cholesterol, and triglyceride levels at the beginning of the study.
(Low Levels of Bad Cholesterol Increase Stroke Risk, The Titi Tudorancea Bulletin)
The low-glycemic index/low-carbohydrate diet resulted in similar insulin sensitivity, systolic blood pressure and HDL and LDL cholesterol levels when compared to the high-glycemic index/high-carbohydrate diet.
(Low-glycemic diets may not improve cardiovascular outcomes when compared to high-glycemic diets, NIH)
Conversely, high levels of high-density lipoprotein (HDL) cholesterol are associated with a lower risk of heart disease.
(Rare mutations reduce heart disease risk, NIH)
Increasing sleep duration or bedtime variability was strongly associated with multiple metabolic and simultaneous problems such as lower HDL cholesterol and higher waist circumference, blood pressure, total triglycerides, and fasting glucose.
(Study links irregular sleep patterns to metabolic disorders, The Titi Tudorancea Bulletin)
Dalcetrapib is structurally dissimilar from other CETP inhibitors, including torcetrapib, and raises functional HDL by a different mechanism.
(Dalcetrapib, NCI Thesaurus)
Bezafibrate decreases triglyceride levels, increases high density lipoprotein (HDL) cholesterol levels, and decreases total and low density lipoprotein (LDL) cholesterol levels.
(Bezafibrate, NCI Thesaurus)
