| Health / Medical Topics |
Heparan Sulfate Proteoglycan
Heparan Sulfate Proteoglycan is an extracellular matrix and vascular basal lamina component. Heparan Sulfate is also an essential co-factor in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. Degradation by heparanase is a key step in extravasation by tumor cells and migrating leukocytes, as well as in angiogenesis, wound healing, and smooth muscle proliferation. In basement membranes, heparan sulfate may stabilize other molecules and influence glomerular permeability and cell adhesion. (From OMIM 142461 and NCI) (NCI Thesaurus)
YOU MAY ALSO LIKE
A nanopolymer-based mouthwash formulation containing a mimetic of the glycosaminoglycan (GAG) heparan sulfate, with potential anti-mucositic and protective activities. Upon rinsing with…
A low molecular weight heparin derivative and heparan sulfate proteoglycan (HSPG) mimetic with no or minimal anticoagulant activity and potential antineoplastic…
Heparan Sulfate Biosynthesis consists of cellular enzymatic reactions that produce heparan sulfate, a glycosaminoglycan of repeating disaccharide units, in most cell plasma…
Heparitin Sulfate. A glycosaminoglycan, structurally similar to heparin but with more N-acetyl groups and fewer O- and N-sulfate groups. Occurs in…
A family of hepatotropic DNA viruses which contains double-stranded DNA genomes and causes hepatitis in humans and animals. Contains two genera: avihepadnavirus…
A SI unit of magnetic permeability equal to one kilogram meter per second squared per ampere squared.
