Hepatoblastoma

Pronunciation

Definition 1

A type of liver tumor that occurs in infants and children. (NCI Dictionary)

Definition 2

A malignant liver neoplasm that occurs almost exclusively in infants, although isolated cases in older children and adults have been reported. Grossly, hepatoblastoma is solid, well circumscribed, and more often solitary than multiple. Microscopically, most of the tumors are composed exclusively of immature hepatocytic elements. About a fourth of hepatoblastomas contain a stromal component that may be undifferentiated or develop into bone or cartilage. The treatment of choice for hepatoblastoma is surgical excision with adjuvant therapy. Liver transplantation is being increasingly used as well. (NCI Thesaurus)

Definition 3

A malignant liver neoplasm composed of immature hepatocytic elements. (NCI Thesaurus/CDISC)

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