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HERPES SIMPLEX VIRUS
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I. (noun)
Sense 1
Meaning:
A herpes virus that affects the skin and nervous system
Synonyms:
herpes simplex; herpes simplex virus
Classified under:
Hypernyms ("herpes simplex virus" is a kind of...):
herpes; herpes virus (any of the animal viruses that cause painful blisters on the skin)
Hyponyms (each of the following is a kind of "herpes simplex virus"):
herpes simplex 1; HS1; HSV-1; HSV-I (a herpes virus that causes oral herpes)
herpes simplex 2; HS2; HSV-2; HSV-II (a herpes virus that can cause genital herpes)
Context examples:
An antiviral agent with activity against herpes simplex viruses and other members of the herpes virus family.
(Phosphonoacetic Acid, NCI Thesaurus)
Localized rash characterized by grouped vesicles or pustules on an erythematous base that is caused by herpes simplex virus infection.
(Herpes Simplex Dermatitis, NCI Thesaurus)
A neuroattenuated, replication-restricted, ICP34.5 deleted (RL1 gene)-mutant herpes simplex virus (HSV) type I, constructed from wild-type strain 17, with potential oncolytic activity.
(Oncolytic HSV1716, NCI Thesaurus)
Glutamine supplements can suppress reactivation of herpes simplex virus (HSV) in mice and guinea pigs.
(Glutamine suppresses herpes in mice and guinea pigs, National Institutes of Health)
A synthetic acyclic guanine derivative with antiviral activity, mainly used to treat infections from herpes simplex virus (HSV) types 1 and 2.
(Penciclovir, NCI Thesaurus)
The sodium salt form of penciclovir, a synthetic acyclic guanine derivative with antiviral activity, mainly used to treat infections from herpes simplex virus (HSV) types 1 and 2.
(Penciclovir Sodium, NCI Thesaurus)
This agent does not require phosphorylation by thymidine kinase (TK) or other kinases and therefore is active in vitro against herpes simplex virus (HSV) TK deficient mutants and cytomegalovirus (CMV) UL97 mutants.
(Foscarnet sodium, NCI Thesaurus)
An adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which, when administered in conjunction with a synthetic acyclic guanosine analogue, possesses potential antineoplastic activity.
(Adenoviral Vector Encoding HSV Thymidine Kinase, NCI Thesaurus)
A gene viral vector complex comprised of a replication-defective adenovirus and a herpes simplex virus thymidine kinase gene that activates ganciclovir, causing inhibition of DNA synthesis and apoptosis.
(Adenovirus RSV-TK, NCI Thesaurus)
An RGD-4C-modified, infectivity-enhanced, bicistronic type 5 adenovirus expressing herpes simplex virus thymidine kinase (HSV-tk) gene, a therapeutic suicide gene, and the somatostatin receptor type 2 (SSTR2) gene with potential antineoplastic activity.
(Ad5.SSTR/TK.RGD, NCI Thesaurus)
