Health / Medical Topics

    HMGB1 Gene

    This gene plays a role in chromatin remodeling, signal transduction and the regulation of gene transcription. It is also involved in the pro-inflammatory response. (NCI Thesaurus)




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    Human HMGB Family Genes encode abundant DNA-binding and bending HMG-Box Family proteins (with structure, rather than sequence, specificity) that play an architectural…
    A fusion protein encoded by the HMGA2/RAD51B fusion gene. This protein is comprised of the AT-hook DNA binding domain of the high…
    A fusion gene that results from a chromosomal translocation t(12;14)(q15;q22-24) which fuses exons 1-3 of the HMGA2 gene to the 3' portion…
    A fusion protein encoded by the HMGA2/LPP fusion gene. This protein is comprised of the AT-hook DNA binding domain of the high…
    A fusion gene that results from a chromosomal translocation t(3;12)(q27-28;q15) which fuses exons 1-3 of the HMGA2 gene to exons 9-11 of…

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