Health / Medical Topics

    Hodgkin Disease

    Pronunciation

    Definition

    A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin disease are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats. Also called Hodgkin lymphoma. (NCI Dictionary)

    More information

    Hodgkin disease is a type of lymphoma. Lymphoma is a cancer of a part of the immune system called the lymph system. The first sign of Hodgkin disease is often an enlarged lymph node. The disease can spread to nearby lymph nodes. Later it may spread to the lungs, liver, or bone marrow. The exact cause is unknown.

    Hodgkin disease is rare. Symptoms include

    • Painless swelling of the lymph nodes in the neck, armpits, or groin
    • Fever and chills
    • Night sweats
    • Weight loss
    • Loss of appetite
    • Itchy skin

    To diagnose Hodgkin disease, doctors use a physical exam and history, blood tests, and a biopsy. Treatment depends on how far the disease has spread. It often includes radiation therapy or chemotherapy.

    The earlier the disease is diagnosed, the more effective the treatment. In most cases, Hodgkin disease can be cured. (NIH: National Cancer Institute)




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