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Homeobox Protein Meis1
Expressed in immunohepatopoietic tissues and in brain by human MEIS1 Gene (TALE/MEIS Family), 390-aa 43-kDa Homeobox Protein MEIS1 contains one homeobox domain, the only conserved motif in the entire protein. Homeobox genes play a crucial role in normal development. Mouse Meis1 regulates Pbx1 protein activity by promoting nuclear import and specifies cell fates and differentiation patterns along the proximodistal limb axis. (NCI Thesaurus)
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