Library / English Dictionary

HYPERTROPHY

Pronunciation (US):

(GB):

Irregular inflected form: hypertrophied   

 I. (noun) 

Sense 1

Meaning:

Abnormal enlargement of a body part or organ

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("hypertrophy" is a kind of...):

dysplasia (abnormal development (of organs or cells) or an abnormal structure resulting from such growth)

Hyponyms (each of the following is a kind of "hypertrophy"):

adenomegaly (gland enlargement)

cor pulmonale (enlargement of the right ventricle of the heart due to disease of the lungs or of the pulmonary blood vessels)

dactylomegaly (abnormally large fingers or toes)

elephantiasis (hypertrophy of certain body parts (usually legs and scrotum); the end state of the disease filariasis)

splenomegaly (an abnormal enlargement of the spleen)

giantism; gigantism; overgrowth (excessive size; usually caused by excessive secretion of growth hormone from the pituitary gland)

acromegalia; acromegaly (enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor))

Derivation:

hypertrophy (undergo hypertrophy)

 II. (verb) 

Sense 1

Meaning:

Undergo hypertrophy

Example:

muscles can hypertrophy when people take steroids

Classified under:

Verbs of grooming, dressing and bodily care

Hypernyms (to "hypertrophy" is one way to...):

grow (become larger, greater, or bigger; expand or gain)

Sentence frame:

Something ----s

Sentence example:

Did his feet hypertrophy?

Derivation:

hypertrophy (abnormal enlargement of a body part or organ)

Credits

 Context examples: 

Alteration in the expression of this gene is associated with development of cardiac hypertrophy.

(MIR208A wt Allele, NCI Thesaurus)

This gene is involved in the regulation of gene expression and plays a role in the development of cardiac hypertrophy.

(MIR208A Gene, NCI Thesaurus)

Factors such as the AKT kinase, reactive oxygen species (ROS) and NE-kB also are involved in signaling that leads to hypertrophy, although their role is not yet clear.

(Cardiac Hypertrophy Pathway, NCI Thesaurus/BIOCARTA)

Dihydrotestosterone suppression is used to treat the symptoms of benign prostatic hypertrophy.

(Dihydrotestosterone Suppression, NCI Thesaurus)

Degrees of cellular hypertrophy and hyperchromasia are variable.

(Atypical Adenomatous Hyperplasia of the Mouse Pulmonary System, NCI Thesaurus/MMHCC)

Also called benign prostatic hypertrophy and BPH.

(Benign prostatic hyperplasia, NCI Dictionary)

It is characterized by lipoatrophy in the trunk, face, and extremities, hypertriglyceridemia, muscle hypertrophy, cardiomyopathy and hepatomegaly.

(Berardinelli-Seip Congenital Lipodystrophy, NCI Thesaurus)

This allele, which encodes MIR1-1 RNA, plays roles in lung and liver cancers, as well as cardiomyopathy, cardiac hypertrophy and coronary artery disease.

(MIR1-1 wt Allele, NCI Thesaurus)

This gene is involved in the regulation of gene expression and plays a role in development of lung and hepatocellular carcinomas, cardiomyopathy, cardiac hypertrophy and coronary artery disease.

(MIR1-1 Gene, NCI Thesaurus)

An electrocardiographic finding suggesting underlying hypertrophy or dilatation of the right atrium.

(P-pulmonale by ECG Finding, NCI Thesaurus)