Immunoconjugate

Pronunciation

Definition 1

An agent that consists of an immune substance, such as a monoclonal antibody, antigen or an immunoglobulin, and covalently bound to other molecule(s), usually either a toxin, a radioisotope, or a cytotoxic agent. Immunoconjugates allow for specific delivery of certain substances to specific cells or tissues for diagnostic or therapeutic purposes. (NCI Thesaurus)

Definition 2

Combinations of diagnostic or therapeutic substances linked with specific immune substances such as immunoglobulins, monoclonal antibodies or antigens. Often the diagnostic or therapeutic substance is a radionuclide. These conjugates are useful tools for specific targeting of drugs and radioisotopes in the chemotherapy and radioimmunotherapy of certain cancers. (NLM, Medical Subject Headings)

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