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IMMUNOTHERAPEUTIC
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I. (adjective)
Sense 1
Meaning:
Of or relating to immunotherapy
Example:
various immunotherapeutic techniques have been employed with AIDS patients
Classified under:
Relational adjectives (pertainyms)
Pertainym:
immunotherapy (therapy designed to produce immunity to a disease or to enhance resistance by the immune system)
Context examples:
A murine IgG1 anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity.
(Anti-CD45 Monoclonal Antibody BC8, NCI Thesaurus)
An attenuated strain of Mycobacterium bovis with non-specific immunoadjuvant and immunotherapeutic properties.
(BCG, NCI Thesaurus)
A measure proposed by Wolchok et al. (Clin Cancer Res 2009;15:7412-7420) to determine the extent of an antitumor response to a particular immunotherapeutic agent.
(Modified Overall Immune Related Response Criterion, NCI Thesaurus)
Autologous Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) that have been genetically modified to express a T-cell chimeric antigen receptor (CAR) targeting the CD19 antigen, with potential immunotherapeutic activity.
(Autologous EBV-CTL CD19CAR zeta, NCI Thesaurus)
A high affinity IgG1 monoclonal antibody with potential immunotherapeutic activity.
(Anti-CD45 Monoclonal Antibody AHN-12, NCI Thesaurus)
As a potential immunotherapeutic agent, recombinant IL-4 also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL).
(Binetrakin, NCI Thesaurus)
An immunotherapeutic agent consisting of a plasmid DNA encoding human Interleukin-2 (IL-2) complexed with a cationic lipid, 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE), in a 5:1 ratio.
(IL-2 Plasmid DNA/Lipid Complex, NCI Thesaurus)
A vaccine containing bacillus Calmette-Guerin (BCG), an attenuated strain of Mycobacterium bovis, with non-specific immunoadjuvant and immunotherapeutic activities.
(BCG Vaccine, NCI Thesaurus)
This multi-antigen/multi-pathway targeting strategy provides broad immunotherapeutic coverage with respect to tumor complexity and heterogeneity and may result in enhanced vaccine efficacy.
(IMT-1012 Immunotherapeutic Vaccine, NCI Thesaurus)
IMT-1012 immunotherapeutic vaccine contains twelve different synthetic peptides or tumor associated antigens (TAAs), including cyclin I (CCNI), cyclin-dependent kinase CDC2, EDDRI and TACE/ADAM17, each of which is involved in a different pathway associated with tumor growth, survival, and metastasis.
(IMT-1012 Immunotherapeutic Vaccine, NCI Thesaurus)
