Library / English Dictionary

    IMPLICATE

    Pronunciation (US): Play  (GB): Play

     I. (verb) 

    Verb forms

    Present simple: I / you / we / they implicate  Listen to US pronunciation  Listen to GB pronunciation ... he / she / it implicates  Listen to US pronunciation  Listen to GB pronunciation

    Past simple: implicated  Listen to US pronunciation  Listen to GB pronunciation

    Past participle: implicated  Listen to US pronunciation  Listen to GB pronunciation

    -ing form: implicating  Listen to US pronunciation  Listen to GB pronunciation

    Sense 1

    Meaning:

    Impose, involve, or imply as a necessary accompaniment or resultplay

    Example:

    What does this move entail?

    Synonyms:

    entail; implicate

    Classified under:

    Verbs of being, having, spatial relations

    Hypernyms (to "implicate" is one way to...):

    lead (tend to or result in)

    Sentence frame:

    Something ----s something

    Derivation:

    implication (something that is inferred (deduced or entailed or implied))

    implication (a meaning that is not expressly stated but can be inferred)

    implication (a logical relation between propositions p and q of the form 'if p then q'; if p is true then q cannot be false)

    Sense 2

    Meaning:

    Bring into intimate and incriminating connectionplay

    Example:

    He is implicated in the scheme to defraud the government

    Classified under:

    Verbs of being, having, spatial relations

    Hypernyms (to "implicate" is one way to...):

    affect; involve; regard (connect closely and often incriminatingly)

    Sentence frames:

    Somebody ----s something
    Somebody ----s somebody
    Something ----s somebody
    Something ----s something

    Derivation:

    implication (an accusation that brings into intimate and usually incriminating connection)

    implication (a relation implicated by virtue of involvement or close connection (especially an incriminating involvement))

    Credits

     Context examples: 

    BlyS, a member of TNF family supporting B-lymphocyte maturation and survival, has been implicated in the pathogenesis of autoimmune diseases and B-lymphocyte malignancies.

    (Belimumab, NCI Thesaurus)

    Inappropriate expression of ARID proteins is increasingly implicated in tumorigenesis.

    (ARID Domain, NCI Thesaurus)

    The gene has also been implicated in the pathogenesis of Alzheimer's disease.

    (APPBP2 Gene, NCI Thesaurus)

    This integral membrane protein may be a new participant in the calcium signal transduction pathway and implicates cyclophilin B in calcium signaling.

    (Calcium Modulating Ligand, NCI Thesaurus)

    CLCA2 has been implicated as a tumor suppressor for breast cancer.

    (Calcium-Activated Chloride Channel-2, NCI Thesaurus)

    Caveolins are also implicated in drug resistance in cancer cells.

    (Caveolin 1, NCI Thesaurus)

    Maria and Julia, and especially Maria, were so closely implicated in Mr. Crawford's misconduct, that she could not give his character, such as she believed it, without betraying them.

    (Mansfield Park, by Jane Austen)

    This gene is involved in immune processes and has been implicated in cancer metastasis.

    (CXCL1 Gene, NCI Thesaurus)

    Overexpression of EGFR, a tyrosine kinase, and its upregulated activity have been implicated in the pathogeneses of several malignancies.

    (Monoclonal Antibody RG 83852, NCI Thesaurus)

    Selectins, containing lectin- and EGF-like domains, are a family of cell adhesion molecules implicated in inflammatory processes and cancer.

    (Pan-Selectin Antagonist GMI-1070, NCI Thesaurus)


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