| Health / Medical Topics |
ING1 wt Allele
Human ING1 wild-type allele is located within 13q34 and is approximately 8 kb in length. This allele, which encodes inhibitor of growth protein 1, plays a role in the induction of p53-mediated apoptosis and modulation of p53-dependent transcriptional activation which results in the inhibition of cell growth. Certain allelic variants of the ING1 gene are associated with the development of squamous cell carcinoma of the head and neck. Expression of the ING1 gene is down-regulated in several types of cancer such as breast cancer, gastric cancer, neuroblastoma and non-small cell lung cancer. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in the regulation of both apoptosis and cell growth.
A reaction to the infusion of pharmacological or biological substances. Symptoms may appear within minutes to hours following the infusion and may…
Leakage of a pharmacologic or a biological substance from the infusion site into the surrounding tissue. Signs and symptoms include induration, erythema,…
The anatomic site through which fluid is introduced into the body.
The volume of a substance injected into a subject in a unit time.
A method of putting fluids, including drugs, into the bloodstream.
