Library / English Dictionary

    INNATE

    Pronunciation (US): Play  (GB): Play

     I. (adjective) 

    Sense 1

    Meaning:

    Present at birth but not necessarily hereditary; acquired during fetal developmentplay

    Synonyms:

    congenital; inborn; innate

    Classified under:

    Adjectives

    Similar:

    nonheritable; noninheritable (not inheritable)

    Derivation:

    innateness (the quality of being innate)

    Sense 2

    Meaning:

    Being talented through inherited qualitiesplay

    Example:

    an innate talent

    Synonyms:

    born; innate; natural

    Classified under:

    Adjectives

    Similar:

    intelligent (having the capacity for thought and reason especially to a high degree)

    Derivation:

    innateness (the quality of being innate)

    Sense 3

    Meaning:

    Not established by conditioning or learningplay

    Example:

    an unconditioned reflex

    Synonyms:

    innate; unconditioned; unlearned

    Classified under:

    Adjectives

    Similar:

    naive (inexperienced)

    Derivation:

    innateness (the quality of being innate)

    Credits

     Context examples: 

    Complement component-4 (1744 aa, ~193 kDa) is part of the complement cascade, which mediates the innate immune response to infection.

    (Complement Component-4, NCI Thesaurus)

    This allele, which encodes beta-defensin 1 protein, plays a role in mediating host defense responses and in innate immunity.

    (DEFB1 wt Allele, NCI Thesaurus)

    This protein is involved in both innate immunity and protein ubiquitination.

    (E3 Ubiquitin/ISG15 Ligase TRIM25, NCI Thesaurus)

    This gene plays a role in innate host defense.

    (ELANE Gene, NCI Thesaurus)

    This allele, which encodes probable ATP-dependent RNA helicase DDX58, is involved in the innate immunity against viruses.

    (DDX58 wt Allele, NCI Thesaurus)

    Specific families of pattern recognition receptors are responsible for detecting foreign DNA from invading microbes or host cells and generating innate immune responses.

    (Cytosolic DNA-Sensing Pathway, NCI Thesaurus/KEGG)

    Through activation of TLR9, this ODN can directly stimulate B-lymphocytes, dendritic and natural killer (NK) cells, resulting in an increase in innate immunity and antibody-dependent cellular cytotoxicity (ADCC).

    (CpG Oligodeoxynucleotide GNKG168, NCI Thesaurus)

    This gene plays a role in the innate immune response.

    (CR2 Gene, NCI Thesaurus)

    Human lactoferrin plays a role in the innate defense of mucosal surfaces and neutrophils.

    (Human Lactoferrin Peptide hLF1-11, NCI Thesaurus)

    In autoinflammatory diseases, the innate immune system, for unknown reasons, becomes activated and triggers inflammation.

    (Diet Affects Autoinflammatory Disease Via Gut Microbes, NIH)


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