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INTACT
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I. (adjective)
Sense 1
Meaning:
Constituting the undiminished entirety; lacking nothing essential especially not damaged
Example:
fought to keep the union intact
Synonyms:
Classified under:
Similar:
whole (including all components without exception; being one unit or constituting the full amount or extent or duration; complete)
Derivation:
intactness (the state of being unimpaired)
Sense 2
Meaning:
Undamaged in any way
Example:
the vase remained intact despite rough handling
Classified under:
Similar:
undamaged (not harmed or spoiled; sound)
Derivation:
intactness (the state of being unimpaired)
Sense 3
Meaning:
(of a woman) having the hymen unbroken
Example:
she was intact, virginal
Synonyms:
intact; inviolate
Classified under:
Adjectives
Similar:
uninjured (not injured physically or mentally)
Derivation:
intactness (the state of being unimpaired)
Sense 4
Meaning:
(used of domestic animals) sexually competent
Example:
an entire horse
Synonyms:
entire; intact
Classified under:
Adjectives
Similar:
uncastrated (not castrated)
Derivation:
intactness (the state of being unimpaired)
Context examples:
Laser-based Raman microspectroscopy is one of only a few tools scientists can use to observe molecular distributions in intact individual cells.
(Cell chemistry illuminated by laser light, National Science Foundation)
Phosphorylation of MARCKS by PKC in intact keratinocytes is not induced during calcium-induced differentiation, but does increase when tested in vitro.
(Calcineurin Pathway, NCI Thesaurus/BIOCARTA)
A genotoxicity study that tests the ability of a substance to cause DNA damage not in intact animals, but in cells or other systems.
(Genotoxicity: In Vitro, NCI Thesaurus/CDISC)
A technique that localizes specific nucleic acid sequences within intact chromosomes, eukaryotic cells, or bacterial cells through the use of specific nucleic acid-labeled probes.
(In Situ Hybridization, NLM, Medical Subject Headings)
The determination of the amount of the intact (containing amino acids 1-42) glucose-dependent insulinotropic peptide present in a sample.
(Intact Glucose-dependent Insulinotropic Peptide Measurement, NCI Thesaurus)
They are transported to the plasma membrane as cleaved, but otherwise intact polypeptides.
(Notch Signaling Pathway, NCI Thesaurus/KEGG)
The histone methyltransferase activity of PRC2 is dependent on an intact SET domain in the EZH2 protein.
(Gene Silencing Pathway, NCI Thesaurus/BIOCARTA)
Endothelin-1 inhibits active Na-K transport by inhibiting Na(+)-K(+)-ATPase in intact renaltubular epithelial cells.
(Endothelin-1, NCI Thesaurus)
Discharge across the cell membrane, into the intracellular space or ducts, of endogenous substances resulting from the activity of intact cells of glands, tissues, or organs.
(Cellular Secretion, NCI Thesaurus)
It involves the resection of the central hepatic segment with the left and right segments remaining intact.
(Central Hepatectomy, NCI Thesaurus)
