Health / Medical Topics

    International Normalized Ratio of Prothrombin Time

    Definition 1

    A measure of the extrinsic pathway of coagulation. The International Normalized Ratio of Prothrombin Time (INR) is the ratio of a patient prothrombin time to a normal (control) sample raised to the power of the International Sensitivity Index (ISI) with a range of 0.8 to 1.2 seconds. (NCI Thesaurus)

    Definition 2

    A ratio that represents the prothrombin time for a plasma specimen, divided by the result for a control plasma specimen, further standardized for the International Sensitivity Index of the tissue factor (thromboplastin) used in the test. (NCI Thesaurus/CDISC)




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