| Health / Medical Topics |
Intraepithelial Neoplasia of the Mouse Mammary Gland
A focal, non-invasive epithelial lesion composed of cells with atypical cytology and/or organization and risk of progressing to malignancy. Biological proof that the lesions are at high risk of malignant transformation depends on identification, isolation and transplantation of the focus into the mammary fat pad. The term Mammary Intraepithelial Neoplasia (MIN) has been recommended by the Annapolis Pathology Panel for all terms under C500148 (focal, atypical mouse mammary lesions). These lesions are identified because they are focal, cytological atypical and associated with mammary cancer in adjacent tissue or glands. (NCI Thesaurus/MMHCC)
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