| Health / Medical Topics |
Intranasal Ketamine
An intranasal formulation of the synthetic cyclohexanone ketamine with analgesic and anesthetic activities. Although its mechanism of action is not well understood, ketamine appears to non-competitively block N-methyl-D-aspartate (NMDA) receptors and agonistically bind to and activate opioid mu and sigma receptors, thereby reducing pain perception, inducing sedation, and producing dissociative anesthesia. (NCI Thesaurus)
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