| Library / English Dictionary |
INVARIANT
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A feature (quantity or property or function) that remains unchanged when a particular transformation is applied to it
Classified under:
Nouns denoting cognitive processes and contents
Hypernyms ("invariant" is a kind of...):
characteristic; feature (a prominent attribute or aspect of something)
Domain category:
math; mathematics; maths (a science (or group of related sciences) dealing with the logic of quantity and shape and arrangement)
II. (adjective)
Sense 1
Meaning:
Unvarying in nature
Example:
principles of unvarying validity
Synonyms:
changeless; constant; invariant; unvarying
Classified under:
Similar:
invariable (not liable to or capable of change)
Derivation:
invariance (the quality of being resistant to variation)
Sense 2
Meaning:
Unaffected by a designated operation or transformation
Classified under:
Similar:
invariable (not liable to or capable of change)
Domain category:
math; mathematics; maths (a science (or group of related sciences) dealing with the logic of quantity and shape and arrangement)
Derivation:
invariance (the nature of a quantity or property or function that remains unchanged when a given transformation is applied to it)
Context examples:
A method to normalize arrays in an AffyBatch using an invariant set, as defined in documents available at http://bioconductor.org/packages/1.9/bioc/html/affy.html
(Bioconductor caAffy Invariant Set Normalization, NCI Thesaurus)
The invariant Glu or Asp at position 12 provides two oxygens for liganding Ca (bidentate ligand).
(Calcium-Binding Domain, NCI Thesaurus)
In calcium-binding proteins, certain invariant hydrophilic loop residues in the HLH motif bind calcium.
(Helix-Loop-Helix Domain, NCI Thesaurus)
The Ii-Key moiety, a 4-amino acid (LRMK) epitope from the MHC class II-associated invariant chain (Ii protein), increases T-helper cell stimulation against HER2/neu antigen when compared to unmodified class II epitopes.
(AE37 Peptide/GM-CSF Vaccine, NCI Thesaurus)
Invariant chain (Ii) associates with newly synthesized class II molecules in the endoplasmic reticulum (ER), an interaction that has been shown to interfere with peptide binding to class II molecules.
(Antigen Presentation Pathway, NCI Thesaurus/BIOCARTA)
Invariant alpha and polymorphic beta chains have glycosylated N-termini, hydrophobic membrane regions, and hydrophilic C-termini.
(HLA-DR Antigen, NCI Thesaurus)
