| Health / Medical Topics |
ISIS 2503
Definition 1
A substance that is being studied in the treatment of cancer. (NCI Dictionary)
Definition 2
A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the oncogene H-Ras. ISIS 2503 selectively inhibits the expression of H-Ras, and may inhibit the growth of some Ras-dependent tumor cells. (NCI Thesaurus)
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Marked fibrosis with cirrhosis is present.
Marked bridging fibrosis with formation of occasional hepatic nodules is present.
Marked bridging fibrosis (portal to portal and porto-central) is present.
Fibrosis extends beyond the portal areas. Occasional portal to portal bridging fibrosis is present.
Minimal fibrosis in most portal areas.
Minimal fibrosis in some portal areas.
