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ISOLATION
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The act of isolating something; setting something apart from others
Synonyms:
Classified under:
Nouns denoting acts or actions
Hypernyms ("isolation" is a kind of...):
separation (the social act of separating or parting company)
Hyponyms (each of the following is a kind of "isolation"):
quarantine (isolation to prevent the spread of infectious disease)
Sense 2
Meaning:
A country's withdrawal from international politics
Example:
he opposed a policy of American isolation
Classified under:
Nouns denoting acts or actions
Hypernyms ("isolation" is a kind of...):
non-engagement; non-involvement; nonparticipation (withdrawing from the activities of a group)
Sense 3
Meaning:
A feeling of being disliked and alone
Classified under:
Nouns denoting feelings and emotions
Hypernyms ("isolation" is a kind of...):
alienation; disaffection; estrangement (the feeling of being alienated from other people)
Sense 4
Meaning:
(psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it
Classified under:
Nouns denoting natural processes
Hypernyms ("isolation" is a kind of...):
defence; defence mechanism; defence reaction; defense; defense mechanism; defense reaction ((psychiatry) an unconscious process that tries to reduce the anxiety associated with instinctive desires)
Domain category:
psychiatry; psychological medicine; psychopathology (the branch of medicine dealing with the diagnosis and treatment of mental disorders)
Derivation:
isolate (separate (experiences) from the emotions relating to them)
Sense 5
Meaning:
A state of separation between persons or groups
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("isolation" is a kind of...):
separation (the state of lacking unity)
Hyponyms (each of the following is a kind of "isolation"):
solitude (the state or situation of being alone)
purdah; solitude (a state of social isolation)
loneliness; solitariness (the state of being alone in solitary isolation)
quarantine (enforced isolation of patients suffering from a contagious disease in order to prevent the spread of disease)
detachment; insularism; insularity; insulation (the state of being isolated or detached)
alienation; estrangement (separation resulting from hostility)
anomie; anomy (personal state of isolation and anxiety resulting from a lack of social control and regulation)
concealment; privacy; privateness; secrecy (the condition of being concealed or hidden)
Derivation:
isolate (place or set apart)
Context examples:
A shared facility which usually provides services for DNA and RNA isolation and DNA cloning and sequencing.
(Nucleic Acid Core Facility, NCI Thesaurus)
The researchers genetically altered the transporter to withstand the temperatures used for isolation.
(Serotonin transporter structure revealed, NIH)
Fortunately it came at a time when there was no distraction; for had it occurred whilst we were at a station, we might not have secured the necessary calm and isolation.
(Dracula, by Bram Stoker)
Cell line established from Chinese hamster ovary cells; used for the isolation of nutritionally deficient mutants and in transfection studies.
(CHO Cells, NIH CRISP Thesaurus)
Isolation of pure liquids by virtue of their different evaporation characteristics.
(Evaporation Purification, NCI Thesaurus)
Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
(Murine Lymphocytes, Tumor-Infiltrating, NCI Thesaurus)
The isolation and analysis of CTCs may thus be a useful method for tracking how cancers evolve during therapy.
(Isolated cancer cells may lead to personalized treatments, NIH)
I look at them, and the only thought which comes to me is a feeling of their isolation and of the impunity with which crime may be committed there.
(The Adventures of Sherlock Holmes, by Sir Arthur Conan Doyle)
Following isolation of lymphocytes, retroviral vector transduction, and expansion of the cells ex vivo, the inducible IL-12/anti-NY-ESO-1 TCR-expressing autologous PBLs are re-administered into the patient by intravenous injection.
(Autologous Peripheral Blood Lymphocytes Cotransduced with Retroviral Vectors Encoding Inducible IL-12 and Anti-NY-ESO-1 TCR, NCI Thesaurus)
Methods of fractionation, isolation, and purification based on the physico-chemical properties of the substance, e.g. crystallization, distillation, solubility (miscibility).
(Chemical Fractionation, NCI Thesaurus)
