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ISOMERASE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
An enzyme that catalyzes its substrate to an isomeric form
Classified under:
Hypernyms ("isomerase" is a kind of...):
enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)
Context examples:
This allele, which encodes protein disulfide-isomerase A3 protein, plays a role in both the rearrangement of protein disulfide bonds and antigen presentation.
(PDIA3 wt Allele, NCI Thesaurus)
This allele, which encodes glucose-6-phosphate isomerase protein, is involved in the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate.
(GPI wt Allele, NCI Thesaurus)
Amorolfine inhibits delta-14-reductase and delta-7,8-isomerase, which depletes ergosterol and causes ignosterol to accumulate in the fungal cytoplasmic cell membrane.
(Amorolfine, NCI Thesaurus)
Enoyl-CoA delta isomerase 2, mitochondrial (394 aa, ~44 kDa) is encoded by the human ECI2 gene.
(Enoyl-CoA Delta Isomerase 2, Mitochondrial, NCI Thesaurus)
To solve this problem, the enzyme enoyl-CoA isomerase moves the first double bond to a position that the beta oxidation enzymes can act on, one carbon closer to the end of the alkyl chain.
(Oxidation of Polyunsaturated Fatty Acid Pathway, NCI Thesaurus/BIOCARTA)
Isomerase Genes encode enzymes (Isomerases) that catalyze spatial or structural changes within a molecule by rearrangement or transfer of specific atoms or moieties to a new intramolecular location to form a new single product.
(Isomerase Gene, NCI Thesaurus)
The enzyme 3,2 enoyl-CoA isomerase moves this double bond closer to the end of the fatty acid chain, where the fatty acid can serve as a substrate for the normal beta-oxidation enzymes to continue beta-oxidation to completion.
(Oxidation of Polyunsaturated Fatty Acid Pathway, NCI Thesaurus/BIOCARTA)
