Ixabepilone

Pronunciation

Definition 1

A drug used to treat metastatic or locally advanced breast cancer that has not improved after treatment with certain other anticancer drugs. It is also being studied in the treatment of other types of cancer. Ixabepilone stops the growth of tumor cells by blocking cell division. It is a type of epothilone analog. Also called BMS-247550 and Ixempra. (NCI Dictionary)

Definition 2

An orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. (NCI Thesaurus)

YOU MAY ALSO LIKE

Iwo Jiman

Denotes the inhabitants of Iwo Jima, a person from there, or their descendants elsewhere.

IVP

A procedure in which x-ray images of the kidneys, ureters, and bladder are taken at regular times after a substance that shows…

IVL wt Allele

Human IVL wild-type allele is located in the vicinity of 1q21 and is approximately 3 kb in length. This allele, which encodes…

IVL Gene

This gene plays a role in keratinization.

Ivermectin

A macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts its anthelmintic effect via activating glutamate-gated chloride channels expressed on…

IV Fluid

A sterile liquid preparation infused into a vein. IV fluid is prescribed as a replacement of fluid, electrolytes, calories, vitamins, and…